ANKS6

Across TCGA patient cohorts, ANKS6 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKS6-associated genes across cancer lineages are RAD51, Cyclin-B1, and p38-MAPK_pT180_Y182. Each is linked with ANKS6 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKS6-to-partner and partner-to-ANKS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by ANKS6-low versus ANKS6-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS6→partner) and Y-score (partner→ANKS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RAD51 →	+0.246	+3.169	.025	.019	3	3
STAD	Cyclin-B1 →	+0.723	+3.169	.001	.019	3	3
UCEC	p38-MAPK_pT180_Y182 →	-0.443	-2.700	.007	.006	3	3
UCEC	PCNA →	+0.194	+2.415	.014	.003	3	3
COAD	Caspase-7-cleavedD198 →	+1.091	+3.593	.001	.001	3	3
STAD	eIF4E →	+0.233	+3.169	.008	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

RAD51 by ANKS6 expression — STAD

Explore this box plot interactively →