ANKS4B

Across TCGA patient cohorts, ANKS4B mutation is significantly associated with the RNA expression of many other genes, with 935 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKS4B-associated genes across cancer lineages are CDADC1, LACTB, and SGTA. Each is linked with ANKS4B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKS4B-to-partner and partner-to-ANKS4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDADC1 grouped by ANKS4B-low versus ANKS4B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS4B→partner) and Y-score (partner→ANKS4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDADC1 →	+0.383	+2.617	.001	<.001	3	2
UCEC	LACTB →	+0.501	+2.447	<.001	.001	3	2
UCEC	SGTA →	+0.521	+2.606	<.001	<.001	3	2
UCEC	RWDD1 →	+0.475	+3.386	<.001	.004	3	2
SKCM	GOT1 →	+0.436	+2.534	.003	.001	3	2
UCEC	NDUFAF4 →	+0.557	+3.617	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 935 associations by consensus.

CDADC1 by ANKS4B expression — UCEC

Explore this box plot interactively →