ANKS4B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKS4B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANKS4B-associated genes across cancer lineages are TP53TG3E, TFAP2D, and TMCO5A. Each is linked with ANKS4B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKS4B-to-partner and partner-to-ANKS4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53TG3E grouped by ANKS4B-low versus ANKS4B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS4B→partner) and Y-score (partner→ANKS4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaTP53TG3E →+0.028+5.209<.001.00531
BLOOD_LymphomaTFAP2D →+0.099+5.643<.001.00231
LARGE_INTESTINETMCO5A →+0.019+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TP53TG3E by ANKS4B expression — BLOOD_Lymphoma

Box plot of TP53TG3E in ANKS4B-low vs ANKS4B-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration