Across TCGA patient cohorts, ANKS1B mutation is significantly associated with the RNA expression of many other genes, with 6,001 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKS1B-associated genes across cancer lineages are TIPIN, HROB, and TRAIP. Each is linked with ANKS1B in more than 4 cancer types. Because this analysis shows association rather than direction, both ANKS1B-to-partner and partner-to-ANKS1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS1B→partner) and Y-score (partner→ANKS1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TIPIN →	+0.573	+2.598	<.001	.005	3	5
UCEC	HROB →	+0.368	+1.362	.002	<.001	3	5
LUSC	TRAIP →	+0.404	+3.181	<.001	<.001	3	5
COAD	DCLRE1A →	+0.442	+3.472	.001	.002	3	4
COAD	ARRDC3-AS1 →	+0.260	+2.080	.005	.004	3	4
COAD	CDC45 →	+0.621	+2.837	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,001 associations by consensus.

Exploration

ANKS1B survival (RNA) · tumor vs normal (RNA) · all ANKS1B data types