Across TCGA pan-cancer cohorts, ANKRD9 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ANKRD9 data layer compared with 23 for mass-spec protein.
The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ANKRD9 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ANKRD9 expression acts as an unfavorable survival marker.
SKCM are the cancer types where ANKRD9 Mutation most reproducibly stratifies survival.