ANKRD66

Across TCGA patient cohorts, ANKRD66 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD66-associated genes across cancer lineages are MTND6P16, RNU6-92P, and RNU6-270P. Each is linked with ANKRD66 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD66-to-partner and partner-to-ANKRD66 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND6P16 grouped by ANKRD66-low versus ANKRD66-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD66→partner) and Y-score (partner→ANKRD66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MTND6P16 →	+0.068	+4.758	<.001	.006	3	2
LIHC	RNU6-92P →	+0.235	+4.544	<.001	.009	3	1
LIHC	RNU6-270P →	+0.264	+4.758	<.001	.006	3	1
LIHC	RNU6-645P →	+0.384	+5.479	<.001	.002	3	1
LIHC	RNA5SP151 →	+0.338	+4.240	.003	.008	3	1
LIHC	RNU6-800P →	+0.524	+5.174	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

MTND6P16 by ANKRD66 expression — LIHC

Explore this box plot interactively →