ANKRD65

Across TCGA patient cohorts, ANKRD65 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD65-associated genes across cancer lineages are MIR4672, RPL31P9, and MIR4500. Each is linked with ANKRD65 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD65-to-partner and partner-to-ANKRD65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4672 grouped by ANKRD65-low versus ANKRD65-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD65→partner) and Y-score (partner→ANKRD65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4672 →	+1.054	+4.947	<.001	<.001	3	1
UCEC	RPL31P9 →	+0.326	+4.453	<.001	.006	3	1
UCEC	MIR4500 →	+0.409	+4.582	.003	.005	3	1
UCEC	RN7SL803P →	+0.326	+3.413	.005	.006	3	1
UCEC	RN7SL660P →	+0.403	+4.400	.002	.001	3	1
UCEC	PRAMEF13 →	+0.072	+4.453	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MIR4672 by ANKRD65 expression — UCEC

Explore this box plot interactively →