ANKRD62

Across TCGA cell cohorts, ANKRD62 mutation is significantly associated with the RNA expression of many other genes, with 215 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD62-associated genes across cancer lineages are C10orf53, CLPS, and ZNF366. Each is linked with ANKRD62 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD62-to-partner and partner-to-ANKRD62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by ANKRD62-low versus ANKRD62-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD62→partner) and Y-score (partner→ANKRD62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C10orf53 →	+0.014	+4.452	.005	.001	3	2
SOFT_TISSUE	CLPS →	+0.092	+4.392	<.001	.004	3	1
OESOPHAGUS	ZNF366 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	SLC5A8 →	+0.070	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUSC	RBMY1E →	+0.820	+4.643	.002	.008	3	1
SKIN	IL25 →	+0.025	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 215 associations by consensus.

C10orf53 by ANKRD62 expression — BLOOD_Lymphoma

Explore this box plot interactively →