ANKRD62

Across TCGA pan-cancer cohorts, ANKRD62 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ANKRD62 data layer compared with 3 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ANKRD62 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ANKRD62 expression acts as an unfavorable survival marker, although some lineages such as UCS and LUSC show a favorable association.

UCS, UVM, and ACC are the cancer types where ANKRD62 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Quartile	II,III,IV	0.868	0.252	.001	54	view →
UVM	DFS	Tertile	II,III,IV	0.227	0.668	<.001	54	view →
ACC	OS	Quartile	II,III,IV	0.620	0.931	<.001	54	view →
KIRP	DFS	Quartile	All	0.454	0.798	<.001	50	view →
UCEC	DFS	Quartile	All	0.477	0.764	<.001	40	view →
READ	DFS	Median	All	0.329	0.679	<.001	34	view →
KICH	DFS	Tertile	All	0.499	0.925	.001	31	view →
THCA	OS	Median	IV	0.581	1.000	.007	27	view →
CHOL	DFS	Median	II,III,IV	0.093	0.510	.002	27	view →
COAD	OS	Quartile	All	0.749	0.900	.005	22	view →
THYM	DFS	Quartile	III,IV	0.324	0.926	.006	12	view →
PAAD	OS	Quartile	II,III,IV	0.365	0.622	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ANKRD62–UCS (OS)

Open the UCS breakdown →