ANKRD62

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD62 mutation is significantly associated with the mutation status of many other genes, with 3,598 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD62-associated genes across cancer lineages are GRM8, PDS5B, and PCDHB2. Each is linked with ANKRD62 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD62-to-partner and partner-to-ANKRD62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRM8 grouped by ANKRD62-low versus ANKRD62-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD62→partner) and Y-score (partner→ANKRD62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYGRM8 →+3.217+3.684.006.00614
OVARYPDS5B →+5.217+4.562<.001<.00114
LARGE_INTESTINEPCDHB2 →+3.182+3.662<.001<.00114
BLOOD_LeukemiaFLNB →+2.285+3.364.006.00614
BLOOD_LeukemiaNLRC5 →+2.378+3.452.005.00514
LUNG_NSCLC_LUADTDRD9 →+4.187+5.000.008.00814
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,598 associations by consensus.

GRM8 by ANKRD62 expression — OVARY

Box plot of GRM8 in ANKRD62-low vs ANKRD62-high samples in OVARY.

Explore this box plot interactively →

Exploration