ANKRD6

Across TCGA patient cohorts, ANKRD6 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD6-associated genes across cancer lineages are mTOR_pS2448, PCNA, and TFRC. Each is linked with ANKRD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD6-to-partner and partner-to-ANKRD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR_pS2448 grouped by ANKRD6-low versus ANKRD6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD6→partner) and Y-score (partner→ANKRD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.117	-2.209	.018	.009	3	2
UCEC	PCNA →	+0.203	+1.874	.005	.002	3	2
UCEC	TFRC →	+0.457	+2.000	.010	.029	3	2
UCEC	4E-BP1 →	+0.255	+2.252	.004	.005	3	2
UCEC	C-Raf →	+0.131	+1.584	.006	.034	3	2
UCEC	EGFR_pY1068 →	-0.222	-1.584	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

mTOR_pS2448 by ANKRD6 expression — UCEC

Explore this box plot interactively →