ANKRD49

Across TCGA patient cohorts, ANKRD49 mutation is significantly associated with the RNA expression of many other genes, with 1,440 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD49-associated genes across cancer lineages are RNA5SP411, VDAC2P1, and RPS29P10. Each is linked with ANKRD49 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD49-to-partner and partner-to-ANKRD49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by ANKRD49-low versus ANKRD49-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD49→partner) and Y-score (partner→ANKRD49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.787	+2.808	<.001	<.001	3	2
COAD	VDAC2P1 →	+0.112	+4.893	.007	.005	3	2
COAD	RPS29P10 →	+0.730	+4.577	<.001	.004	3	2
COAD	MTCYBP10 →	+0.162	+4.602	<.001	.008	3	2
PRAD	OR8I2 →	+0.049	+7.939	<.001	.008	3	2
BLCA	OR5W2 →	+0.054	+5.033	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,440 associations by consensus.

RNA5SP411 by ANKRD49 expression — UCEC

Explore this box plot interactively →