Across TCGA patient cohorts, ANKRD46 mutation is significantly associated with the RNA expression of many other genes, with 511 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD46-associated genes across cancer lineages are THUMPD1P1, AIMP1P2, and RNA5SP473. Each is linked with ANKRD46 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD46-to-partner and partner-to-ANKRD46 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD46→partner) and Y-score (partner→ANKRD46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	THUMPD1P1 →	+0.097	+3.393	<.001	.003	3	2
SKCM	AIMP1P2 →	+0.095	+4.147	<.001	.008	3	2
SKCM	RNA5SP473 →	+0.476	+3.983	<.001	.002	3	2
UCEC	RNU6-222P →	+0.602	+2.961	<.001	.002	3	2
UCEC	PRDX2P2 →	+0.271	+3.032	<.001	.002	3	2
UCEC	MTATP6P21 →	+0.255	+2.704	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 511 associations by consensus.

Exploration

ANKRD46 survival (RNA) · tumor vs normal (RNA) · all ANKRD46 data types