ANKRD44

Across TCGA cell cohorts, ANKRD44 mutation is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD44-associated genes across cancer lineages are FAM149A, MAGEB4, and AFG1L. Each is linked with ANKRD44 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD44-to-partner and partner-to-ANKRD44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM149A grouped by ANKRD44-low versus ANKRD44-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD44→partner) and Y-score (partner→ANKRD44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM149A →	+1.844	+3.237	<.001	.003	3	1
LARGE_INTESTINE	MAGEB4 →	+0.009	+3.192	<.001	.002	3	1
LARGE_INTESTINE	AFG1L →	+0.594	+3.212	.001	.006	3	1
LARGE_INTESTINE	COPS2 →	+0.615	+3.212	.001	.006	3	1
LARGE_INTESTINE	PXMP2 →	+0.595	+3.212	.008	.006	3	1
LARGE_INTESTINE	ALKBH2 →	+0.767	+3.212	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

FAM149A by ANKRD44 expression — LARGE_INTESTINE

Explore this box plot interactively →