ANKRD44-IT1

Across TCGA pan-cancer cohorts, ANKRD44-IT1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated ANKRD44-IT1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ANKRD44-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ANKRD44-IT1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and ESCA show a favorable association.

ACC, LUSC, and ESCA are the cancer types where ANKRD44-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Quartile	II,III,IV	0.571	0.861	.004	54	view →
LUSC	DFS	Quartile	III,IV	0.906	0.554	<.001	43	view →
ESCA	DFS	Quartile	II,III,IV	0.654	0.348	.001	41	view →
OV	DFS	Tertile	II,III,IV	0.414	0.304	.002	36	view →
PAAD	OS	Tertile	II,III,IV	0.725	0.434	<.001	34	view →
KIRC	OS	Tertile	All	0.551	0.740	<.001	33	view →
LUAD	DFS	Median	All	0.838	0.742	.002	29	view →
BRCA	OS	Tertile	All	0.955	0.915	.009	27	view →
KICH	DFS	Median	III,IV	0.240	1.000	.001	27	view →
DLBC	OS	Median	III,IV	0.359	0.797	.005	21	view →
TGCT	DFS	Median	II,III,IV	0.757	1.000	.030	16	view →
SARC	DFS	Quartile	All	0.606	0.436	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

ANKRD44-IT1–ACC (OS)

Open the ACC breakdown →