ANKRD44-IT1

Across TCGA pan-cancer cohorts, ANKRD44-IT1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of ANKRD44-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where ANKRD44-IT1 RNA is repressed in tumor relative to normal tissue. In most cancer types ANKRD44-IT1 is over-expressed in tumor, although a few such as LUSC and PAAD show the opposite, repressed pattern.

LUSC, PAAD, and THCA are the cancer types where ANKRD44-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD44-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−0.205	<.001	5	view →
PAAD	Male	All	−0.090	.012	2	view →
THCA	All	All	−0.073	.011	2	view →
LIHC	All	II,III,IV	+0.045	.023	1	view →
HNSC	Male	II,III,IV	+0.044	.046	1	view →
KIRC	All	All	+0.039	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

ANKRD44-IT1–LUSC

Open the LUSC breakdown →