ANKRD44-AS1

Across TCGA pan-cancer cohorts, ANKRD44-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ANKRD44-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ANKRD44-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ANKRD44-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, BRCA, and SKCM are the cancer types where ANKRD44-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.773	0.620	<.001	121	view →
BRCA	OS	Tertile	All	0.707	0.488	<.001	83	view →
SKCM	OS	Median	All	0.417	0.282	<.001	82	view →
LGG	DFS	Tertile	All	0.616	0.785	<.001	48	view →
CESC	OS	Median	II,III,IV	0.679	0.342	.002	38	view →
BLCA	DFS	Tertile	All	0.579	0.443	.018	26	view →
UCEC	OS	Tertile	All	0.964	0.894	.005	24	view →
ESCA	DFS	Quartile	III,IV	0.653	0.281	.010	23	view →
LUSC	OS	Tertile	III,IV	0.690	0.422	.009	22	view →
STAD	DFS	Median	IV	0.626	0.201	.006	21	view →
MESO	DFS	Median	All	0.670	0.230	.001	21	view →
THYM	OS	Median	All	0.965	0.741	.005	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ANKRD44-AS1–HNSC (DFS)

Open the HNSC breakdown →