ANKRD44-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ANKRD44-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ANKRD44-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ANKRD44-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ANKRD44-AS1 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, COAD, and LUSC are the cancer types where ANKRD44-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ANKRD44-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHAllIII,IV−0.894<.00110view →
COADAllII,III,IV−0.411<.0019view →
LUSCMaleIII,IV−3.880<.0018view →
LUADAllIII,IV−2.157<.0018view →
THCAAllII,III,IV−0.298.0085view →
BLCAAllAll−1.229.0034view →
CHOLAllAll+0.425<.0013view →
BRCAAllIV−0.520.0172view →
STADFemaleIII,IV+1.230.0431view →
READAllAll−0.566.0191view →
HNSCMaleII,III,IV−0.305.0471view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ANKRD44-AS1–KICH

Tumor-vs-normal expression box plot for ANKRD44-AS1 RNA in KICH.

Open the KICH breakdown →

Exploration