ANKRD42

Across TCGA patient cohorts, ANKRD42 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD42-associated genes across cancer lineages are FoxM1, RAD51, and ATM. Each is linked with ANKRD42 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD42-to-partner and partner-to-ANKRD42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by ANKRD42-low versus ANKRD42-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD42→partner) and Y-score (partner→ANKRD42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.202	+1.807	.022	.004	3	3
UCEC	RAD51 →	+0.094	+1.700	.048	.040	3	3
UCEC	ATM →	-0.448	-2.687	.003	.005	3	3
UCEC	Caspase-7-cleavedD198 →	+0.859	+4.169	<.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.800	+2.523	<.001	<.001	3	3
SKCM	Stathmin →	+0.266	+2.832	.006	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

FoxM1 by ANKRD42 expression — UCEC

Explore this box plot interactively →