ANKRD42

Across TCGA cell cohorts, ANKRD42 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,868 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANKRD42-associated GO terms across cancer lineages are Positive regulation of autophagy, Protein localization to cilium, and Golgi to plasma membrane protein transport. Each is linked with ANKRD42 in more than 13 cancer types. Because this analysis shows association rather than direction, both ANKRD42-to-partner and partner-to-ANKRD42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by ANKRD42-low versus ANKRD42-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD42→partner) and Y-score (partner→ANKRD42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of autophagy →	+0.048	+0.635	<.001	.002	3	13
LARGE_INTESTINE	Protein localization to cilium →	+0.049	+0.527	<.001	.001	3	13
STOMACH	Golgi to plasma membrane protein transport →	+0.113	+0.858	.006	.008	2	14
BLOOD_Lymphoma	Positive regulation of macroautophagy →	+0.052	+0.820	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to plasma membrane →	+0.094	+0.770	.002	.007	2	13
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.063	+0.793	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,868 associations by consensus.

Positive regulation of autophagy by ANKRD42 expression — KIDNEY

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