ANKRD36C

Across TCGA pan-cancer cohorts, ANKRD36C Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated ANKRD36C data layer compared with 26 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ANKRD36C Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ANKRD36C expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, READ, and ACC are the cancer types where ANKRD36C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.941	0.425	.004	34	view →
READ	OS	Median	II,III,IV	0.111	0.919	<.001	33	view →
ACC	DFS	Median	All	0.093	0.674	<.001	30	view →
BLCA	DFS	Median	IV	0.095	0.472	<.001	18	view →
HNSC	DFS	Median	All	0.195	0.710	.019	18	view →
COAD	DFS	Median	II,III,IV	0.359	0.653	.020	12	view →
LIHC	OS	Median	All	0.396	0.787	.011	6	view →
SKCM	DFS	Median	All	1.000	0.213	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

ANKRD36C–UCEC (DFS)

Open the UCEC breakdown →