Across TCGA patient cohorts, ANKRD35 mutation is significantly associated with the RNA expression of many other genes, with 3,761 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD35-associated genes across cancer lineages are RNA5SP346, RNF126, and DAZAP1. Each is linked with ANKRD35 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD35-to-partner and partner-to-ANKRD35 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD35→partner) and Y-score (partner→ANKRD35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNA5SP346 →	+0.313	+7.939	<.001	.008	3	3
UCEC	RNF126 →	+0.454	+4.119	<.001	<.001	3	3
UCEC	DAZAP1 →	+0.369	+2.295	<.001	<.001	3	3
HNSC	ATP5MC1P8 →	+0.367	+4.197	<.001	.009	3	3
UCEC	RNU4-58P →	+0.193	+2.481	<.001	<.001	3	3
LUSC	SLC26A6 →	+0.561	+3.807	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Exploration

ANKRD35 survival (RNA) · tumor vs normal (RNA) · all ANKRD35 data types