ANKRD34C

Across TCGA patient cohorts, ANKRD34C mutation is significantly associated with the RNA expression of many other genes, with 4,462 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD34C-associated genes across cancer lineages are TRDV3, BNIP3P4, and OR6U2P. Each is linked with ANKRD34C in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD34C-to-partner and partner-to-ANKRD34C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRDV3 grouped by ANKRD34C-low versus ANKRD34C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD34C→partner) and Y-score (partner→ANKRD34C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRDV3 →	+0.710	+1.915	<.001	.004	3	3
UCEC	BNIP3P4 →	+0.041	+1.982	<.001	.004	3	2
LIHC	OR6U2P →	+0.233	+4.523	<.001	<.001	3	2
READ	CGB2 →	+0.621	+4.804	<.001	<.001	3	2
READ	GOLGA8Q →	+0.045	+3.813	.003	.008	3	2
READ	RNU6-176P →	+0.278	+4.672	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,462 associations by consensus.

TRDV3 by ANKRD34C expression — COAD

Explore this box plot interactively →