ANKRD34A

Across TCGA pan-cancer cohorts, ANKRD34A Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ANKRD34A data layer compared with 23 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher ANKRD34A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ANKRD34A expression acts as an unfavorable survival marker.

THYM, KIRC, and LGG are the cancer types where ANKRD34A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
KIRC	DFS	Median	III,IV	0.203	0.744	.025	24	view →
LGG	OS	Median	All	0.128	0.811	<.001	12	view →
STAD	OS	Median	III,IV	0.003	0.633	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ANKRD34A–THYM (OS)

Open the THYM breakdown →