ANKRD34A

Across TCGA patient cohorts, ANKRD34A protein abundance is significantly associated with the RNA expression of many other genes, with 1,191 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANKRD34A-associated genes across cancer lineages are PIGH, CHD8, and PCK2. Each is linked with ANKRD34A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD34A-to-partner and partner-to-ANKRD34A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANKRD34A versus PIGH in LSCC, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD34A→partner) and Y-score (partner→ANKRD34A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIGH →	-0.865	-1.388	.003	.004	3	1
LSCC	CHD8 →	-0.878	-1.388	.007	.004	3	1
LSCC	PCK2 →	-1.599	-2.066	<.001	.002	3	1
LSCC	EMC9 →	-0.891	-1.388	.006	.004	3	1
LSCC	CDK5RAP1 →	-0.976	-1.388	.008	.004	3	1
LSCC	SCML2 →	-2.469	-2.066	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,191 associations by consensus.

ANKRD34A vs PIGH — LSCC

Explore this scatter interactively →