ANKRD33B

Across TCGA cell cohorts, ANKRD33B mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible ANKRD33B-associated genes across cancer lineages are MMP27, OR1L3, and NLRP8. Each is linked with ANKRD33B in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD33B-to-partner and partner-to-ANKRD33B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by ANKRD33B-low versus ANKRD33B-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD33B→partner) and Y-score (partner→ANKRD33B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MMP27 →	+0.006	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	OR1L3 →	+0.060	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	NLRP8 →	+0.023	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	FAM47B →	+0.036	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	OR2W5 →	+0.046	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	PRAMEF14 →	+0.090	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

MMP27 by ANKRD33B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →