ANKRD33

Across TCGA patient cohorts, ANKRD33 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,715 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ANKRD33-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Positive regulation of DNA metabolic process, and Endosome organization. Each is linked with ANKRD33 in more than 15 cancer types. Because this analysis shows association rather than direction, both ANKRD33-to-partner and partner-to-ANKRD33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by ANKRD33-low versus ANKRD33-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD33→partner) and Y-score (partner→ANKRD33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of post-translational protein modification →	+0.088	+0.234	<.001	<.001	3	16
STAD	Positive regulation of DNA metabolic process →	+0.086	+0.243	<.001	<.001	3	15
STAD	Endosome organization →	+0.056	+0.185	<.001	<.001	3	15
STAD	Establishment of protein localization to membrane →	+0.064	+0.160	<.001	.001	2	15
STAD	Negative regulation of apoptotic signaling pathway →	+0.051	+0.177	<.001	<.001	3	14
STAD	Response to endoplasmic reticulum stress →	+0.082	+0.206	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,715 associations by consensus.

Regulation of post-translational protein modification by ANKRD33 expression — STAD

Explore this box plot interactively →