ANKRD33

Across TCGA patient cohorts, ANKRD33 mutation is significantly associated with the RNA expression of many other genes, with 5,441 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD33-associated genes across cancer lineages are PRC1, RNFT2, and SPC24. Each is linked with ANKRD33 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD33-to-partner and partner-to-ANKRD33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRC1 grouped by ANKRD33-low versus ANKRD33-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD33→partner) and Y-score (partner→ANKRD33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRC1 →	+0.925	+2.584	<.001	<.001	3	4
LUAD	RNFT2 →	+0.833	+3.471	<.001	.002	3	4
LUAD	SPC24 →	+1.020	+2.819	<.001	.001	3	4
UCEC	PSMC3IP →	+0.831	+2.595	<.001	<.001	3	4
LUAD	FCER1A →	-1.487	-2.795	.001	.003	3	3
UCEC	PRF1 →	+1.035	+2.745	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,441 associations by consensus.

PRC1 by ANKRD33 expression — UCEC

Explore this box plot interactively →