ANKRD33

Across TCGA cell cohorts, ANKRD33 RNA expression is significantly associated with the go_rna of many other GO terms, with 182 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD33-associated GO terms across cancer lineages are Regulation of membrane protein ectodomain proteolysis, Glomerular endothelium development, and Mating behavior. Each is linked with ANKRD33 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD33-to-partner and partner-to-ANKRD33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of membrane protein ectodomain proteolysis grouped by ANKRD33-low versus ANKRD33-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD33→partner) and Y-score (partner→ANKRD33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of membrane protein ectodomain proteolysis →	+0.100	+0.427	<.001	.007	3	3
SOFT_TISSUE	Glomerular endothelium development →	+1.055	+0.034	<.001	.003	3	2
SOFT_TISSUE	Mating behavior →	-0.163	-0.049	<.001	.002	3	2
SOFT_TISSUE	Regulation of potassium ion transmembrane transport →	-0.094	-0.061	.003	.002	3	2
SOFT_TISSUE	Stress-activated protein kinase signaling cascade →	+0.065	+0.056	.003	.007	3	2
LARGE_INTESTINE	Sperm flagellum assembly →	-0.022	-0.112	.001	.001	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 182 associations by consensus.

Regulation of membrane protein ectodomain proteolysis by ANKRD33 expression — OVARY

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