ANKRD33

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD33 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible ANKRD33-associated genes across cancer lineages are MYH1, PNLIPRP1, and DPRX. Each is linked with ANKRD33 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD33-to-partner and partner-to-ANKRD33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH1 grouped by ANKRD33-low versus ANKRD33-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD33→partner) and Y-score (partner→ANKRD33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASMYH1 →+0.029+5.000<.001.00631
PANCREASPNLIPRP1 →+0.049+5.000<.001.00631
PANCREASDPRX →+0.073+5.614<.001.00231
PANCREASC8B →+0.006+5.614<.001.00231
PANCREASGPX5 →+0.015+5.000.008.00631
PANCREASMYH4 →+0.026+5.000<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MYH1 by ANKRD33 expression — PANCREAS

Box plot of MYH1 in ANKRD33-low vs ANKRD33-high samples in PANCREAS.

Explore this box plot interactively →

Exploration