ANKRD31

Across TCGA patient cohorts, ANKRD31 mutation is significantly associated with the RNA expression of many other genes, with 3,895 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD31-associated genes across cancer lineages are RNVU1-28, RNU6-863P, and RNA5SP413. Each is linked with ANKRD31 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD31-to-partner and partner-to-ANKRD31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNVU1-28 grouped by ANKRD31-low versus ANKRD31-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD31→partner) and Y-score (partner→ANKRD31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNVU1-28 →	+0.549	+1.355	<.001	.008	3	2
UCEC	RNU6-863P →	+0.211	+1.573	.004	.007	3	2
UCEC	RNA5SP413 →	+0.927	+1.614	<.001	.002	3	2
UCEC	INSL4 →	+0.730	+1.753	<.001	.001	3	2
SCLC	C3orf84 →	+0.192	+4.693	.001	.002	3	1
BRCA	MIR7159 →	+0.466	+5.317	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,895 associations by consensus.

RNVU1-28 by ANKRD31 expression — UCEC

Explore this box plot interactively →