ANKRD31

Across TCGA patient cohorts, ANKRD31 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD31-associated genes across cancer lineages are 14-3-3_beta, A-Raf_pS299, and JNK_pT183_Y185. Each is linked with ANKRD31 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD31-to-partner and partner-to-ANKRD31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by ANKRD31-low versus ANKRD31-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD31→partner) and Y-score (partner→ANKRD31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.100	-2.088	.004	.016	3	1
UCEC	A-Raf_pS299 →	-0.123	-3.459	.003	.005	3	1
UCEC	JNK_pT183_Y185 →	-0.133	-1.584	.023	.034	3	1
UCEC	JNK2 →	+0.210	+3.727	.002	<.001	3	1
UCEC	Ku80 →	+0.226	+1.750	.005	.004	3	1
UCEC	MEK1 →	+0.301	+2.169	.017	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

14-3-3_beta by ANKRD31 expression — UCEC

Explore this box plot interactively →