ANKRD30B

Across TCGA patient cohorts, ANKRD30B mutation is significantly associated with the RNA expression of many other genes, with 5,038 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD30B-associated genes across cancer lineages are C9orf50, HMBS, and EMC6. Each is linked with ANKRD30B in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKRD30B-to-partner and partner-to-ANKRD30B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf50 grouped by ANKRD30B-low versus ANKRD30B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD30B→partner) and Y-score (partner→ANKRD30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C9orf50 →	-0.339	-2.050	<.001	<.001	3	4
SKCM	HMBS →	+0.450	+2.119	.001	.003	3	4
COAD	EMC6 →	+0.430	+3.361	.009	.004	3	4
UCEC	DOHH →	+0.455	+2.101	<.001	<.001	3	4
COAD	IMPA2 →	+0.510	+2.026	.001	.005	3	4
UCEC	KLC2 →	+0.329	+1.404	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,038 associations by consensus.

C9orf50 by ANKRD30B expression — UCEC

Explore this box plot interactively →