ANKRD30B

Across TCGA pan-cancer cohorts, ANKRD30B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ANKRD30B data layer compared with 12 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ANKRD30B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ANKRD30B expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

KIRC, KIRP, and UVM are the cancer types where ANKRD30B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.511	0.711	<.001	185	view →
KIRP	OS	Median	All	0.517	0.792	<.001	106	view →
UVM	DFS	Median	All	0.317	0.770	<.001	98	view →
DLBC	DFS	Median	IV	0.136	0.914	<.001	97	view →
LUAD	OS	Median	II,III,IV	0.586	0.774	<.001	64	view →
KICH	OS	Quartile	All	0.567	0.963	.001	48	view →
UCS	OS	Median	II,III,IV	0.647	0.252	.013	38	view →
SCLC	DFS	Tertile	II,III,IV	0.164	0.814	<.001	30	view →
HNSC	OS	Tertile	III,IV	0.498	0.749	.001	28	view →
LUSC	OS	Tertile	II,III,IV	0.497	0.852	<.001	22	view →
THCA	DFS	Median	II,III,IV	0.597	0.895	.002	22	view →
BLCA	OS	Tertile	IV	0.144	0.364	.013	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ANKRD30B–KIRC (OS)

Open the KIRC breakdown →