ANKRD30B

Across TCGA patient cohorts, ANKRD30B mutation is significantly associated with the total protein of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD30B-associated genes across cancer lineages are ASNS, CD31, and Smad4. Each is linked with ANKRD30B in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD30B-to-partner and partner-to-ANKRD30B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ANKRD30B-low versus ANKRD30B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD30B→partner) and Y-score (partner→ANKRD30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.480	+2.321	.001	.032	3	3
UCEC	CD31 →	-0.085	-1.343	.024	.013	3	3
LUAD	Smad4 →	-0.111	-3.305	.032	.010	3	2
LUSC	YAP_pS127 →	+0.338	+2.331	.031	.019	3	2
UCEC	eIF4E →	+0.159	+1.547	.003	<.001	3	2
UCEC	JNK_pT183_Y185 →	-0.116	-1.392	.006	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

ASNS by ANKRD30B expression — COAD

Explore this box plot interactively →