ANKRD30B

Across TCGA cell cohorts, ANKRD30B mutation is significantly associated with the RNA expression of many other genes, with 511 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ANKRD30B-associated genes across cancer lineages are RETNLB, C4orf17, and KRTAP19-1. Each is linked with ANKRD30B in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD30B-to-partner and partner-to-ANKRD30B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RETNLB grouped by ANKRD30B-low versus ANKRD30B-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD30B→partner) and Y-score (partner→ANKRD30B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RETNLB →	+0.180	+5.169	<.001	.004	3	2
OESOPHAGUS	C4orf17 →	+0.070	+3.459	.007	.006	3	2
OESOPHAGUS	KRTAP19-1 →	+0.677	+3.115	.001	.005	3	2
OESOPHAGUS	KRTAP7-1 →	+0.085	+3.273	<.001	.004	3	2
STOMACH	IFNL4 →	+0.131	+3.830	.001	.005	3	2
LUNG_SCLC	CNNM2 →	+0.568	+3.082	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 511 associations by consensus.

RETNLB by ANKRD30B expression — BONE

Explore this box plot interactively →