ANKRD29

Across TCGA patient cohorts, ANKRD29 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD29-associated genes across cancer lineages are FOXO3a_pS318_S321, HER3, and Acetyl-a-Tubulin-Lys40. Each is linked with ANKRD29 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD29-to-partner and partner-to-ANKRD29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXO3a_pS318_S321 grouped by ANKRD29-low versus ANKRD29-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD29→partner) and Y-score (partner→ANKRD29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.192	-3.321	.003	.010	3	1
UCEC	HER3 →	+0.401	+2.183	.005	.035	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.713	+3.009	.007	.019	3	1
UCEC	ERK2 →	+0.316	+3.321	.001	.010	2	1
UCEC	mTOR_pS2448 →	-0.226	-3.321	.003	.010	2	1
UCEC	C-Raf_pS338 →	-0.125	-3.321	.003	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

FOXO3a_pS318_S321 by ANKRD29 expression — UCEC

Explore this box plot interactively →