ANKRD29

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANKRD29 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ANKRD29-associated genes across cancer lineages are NEU2, ACER1, and PRAMEF20. Each is linked with ANKRD29 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD29-to-partner and partner-to-ANKRD29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NEU2 grouped by ANKRD29-low versus ANKRD29-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD29→partner) and Y-score (partner→ANKRD29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINENEU2 →+0.028+4.054<.001.00431
LARGE_INTESTINEACER1 →+0.096+3.823.001.00631
LARGE_INTESTINEPRAMEF20 →+0.012+4.437<.001.00431
LARGE_INTESTINEMOG →+0.146+4.054<.001.00431
CNSTEX55 →+0.037+4.321<.001.00931
CNSOR11H6 →+0.016+4.321.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

NEU2 by ANKRD29 expression — LARGE_INTESTINE

Box plot of NEU2 in ANKRD29-low vs ANKRD29-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration