ANKRD28

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD28 mutation is significantly associated with the RNA expression of many other genes, with 2,229 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD28-associated genes across cancer lineages are DUSP15, CENPU, and SKA1. Each is linked with ANKRD28 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD28-to-partner and partner-to-ANKRD28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD28→partner) and Y-score (partner→ANKRD28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDUSP15 →-0.531-2.097.005.00132
UCECCENPU →+0.454+1.969.006.00232
UCECSKA1 →+0.620+2.247<.001<.00132
UCECCXCL13 →+2.040+2.502<.001<.00132
UCECCCNB2 →+0.510+1.784.002<.00132
UCECFCER1G →+0.826+1.784<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,229 associations by consensus.

Exploration