ANKRD28

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD28 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD28-associated genes across cancer lineages are GAPDH, INPP4B, and JNK2. Each is linked with ANKRD28 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD28-to-partner and partner-to-ANKRD28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD28→partner) and Y-score (partner→ANKRD28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGAPDH →+0.330+1.700.047.04032
UCECINPP4B →-0.242-2.321.015<.00132
UCECJNK2 →+0.201+1.495.001.03432
UCECPCNA →+0.178+1.502.007.02732
COADPDCD4 →-0.578-2.991.008.03632
UCECATM →-0.474-2.169<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

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