ANKRD27

Across TCGA patient cohorts, ANKRD27 mutation is significantly associated with the RNA expression of many other genes, with 3,747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD27-associated genes across cancer lineages are RNU6-662P, CENPU, and BIRC5. Each is linked with ANKRD27 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANKRD27-to-partner and partner-to-ANKRD27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-662P grouped by ANKRD27-low versus ANKRD27-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD27→partner) and Y-score (partner→ANKRD27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-662P →	+0.269	+5.149	<.001	.003	3	3
UCEC	CENPU →	+0.637	+1.617	<.001	<.001	3	3
UCEC	BIRC5 →	+0.547	+1.334	.001	.001	3	3
UCEC	NDUFA6 →	+0.512	+2.470	<.001	<.001	3	3
UCEC	LINC01715 →	+0.229	+1.857	<.001	<.001	3	3
LUAD	RPL23AP40 →	+0.458	+4.336	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,747 associations by consensus.

RNU6-662P by ANKRD27 expression — LIHC

Explore this box plot interactively →