ANKRD27

Across TCGA cell cohorts, ANKRD27 mutation is significantly associated with the RNA expression of many other genes, with 303 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD27-associated genes across cancer lineages are HSD3B2, FAM183A, and LYZL6. Each is linked with ANKRD27 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD27-to-partner and partner-to-ANKRD27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSD3B2 grouped by ANKRD27-low versus ANKRD27-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD27→partner) and Y-score (partner→ANKRD27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HSD3B2 →	+0.012	+3.169	<.001	.008	3	2
LARGE_INTESTINE	FAM183A →	+0.530	+3.212	<.001	.006	3	2
SOFT_TISSUE	LYZL6 →	+0.019	+5.369	<.001	.004	3	1
OESOPHAGUS	KRTAP1-4 →	+0.143	+4.906	<.001	.006	3	1
LUNG_SCLC	IFNA16 →	+0.289	+5.029	<.001	.006	3	1
LUNG_SCLC	KRTAP4-6 →	+0.070	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 303 associations by consensus.

HSD3B2 by ANKRD27 expression — BLOOD_Lymphoma

Explore this box plot interactively →