ANKRD26P1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKRD26P1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD26P1-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and A-Raf_pS299. Each is linked with ANKRD26P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD26P1-to-partner and partner-to-ANKRD26P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by ANKRD26P1-low versus ANKRD26P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD26P1→partner) and Y-score (partner→ANKRD26P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.095-2.295.016.03331
UCECEGFR_pY1068 →-0.305-3.459.001.00531
UCECA-Raf_pS299 →-0.153-2.807.001.00331
UCECGAPDH →+0.478+2.459.023.01831
UCECACC1 →+0.351+2.335.013.01831
UCECHeregulin →-0.126-2.000.009.03031
Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

14-3-3_beta by ANKRD26P1 expression — UCEC

Box plot of 14-3-3_beta in ANKRD26P1-low vs ANKRD26P1-high samples in UCEC.

Explore this box plot interactively →

Exploration