Across TCGA pan-cancer cohorts, ANKRD26P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ANKRD26P1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ANKRD26P1 RNA is repressed in tumor relative to normal tissue. In most cancer types ANKRD26P1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
KIRC and COAD are the cancer types where ANKRD26P1 tumor–normal differential expression is most reproducible.