ANKRD24

Across TCGA patient cohorts, ANKRD24 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKRD24-associated genes across cancer lineages are MSH2, p27_pT198, and PCNA. Each is linked with ANKRD24 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD24-to-partner and partner-to-ANKRD24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH2 grouped by ANKRD24-low versus ANKRD24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD24→partner) and Y-score (partner→ANKRD24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH2 →	-0.223	-3.433	.006	.005	3	2
UCEC	p27_pT198 →	+0.103	+3.169	.006	.018	3	2
UCEC	PCNA →	+0.185	+1.362	.015	.037	3	2
SKCM	GSK3-a-b →	-0.202	-3.136	.002	.018	3	1
SKCM	NDRG1_pT346 →	-0.633	-2.222	.022	.010	3	1
SKCM	PDK1_pS241 →	-0.205	-1.683	.003	.043	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

MSH2 by ANKRD24 expression — UCEC

Explore this box plot interactively →