ANKRD24

Across TCGA pan-cancer cohorts, ANKRD24 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ANKRD24 data layer compared with 7 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ANKRD24 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ANKRD24 expression acts as an unfavorable survival marker, although some lineages such as LIHC and BRCA show a favorable association.

COAD, LIHC, and BRCA are the cancer types where ANKRD24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	II,III,IV	0.706	0.859	<.001	138	view →
LIHC	OS	Median	All	0.761	0.611	<.001	61	view →
BRCA	OS	Quartile	III,IV	0.911	0.718	.002	52	view →
BLCA	OS	Median	All	0.496	0.350	.007	38	view →
SKCM	OS	Tertile	All	0.428	0.242	<.001	37	view →
LAML	DFS	Median	All	0.337	0.573	<.001	30	view →
LGG	OS	Tertile	All	0.932	0.840	.002	26	view →
CESC	OS	Quartile	All	0.936	0.771	.001	26	view →
UCS	OS	Tertile	IV	0.156	1.000	.024	24	view →
DLBC	DFS	Median	All	0.331	0.871	.008	22	view →
CHOL	DFS	Tertile	II,III,IV	0.198	0.607	.006	17	view →
SARC	DFS	Median	All	0.725	0.457	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ANKRD24–COAD (OS)

Open the COAD breakdown →