ANKRD24

Across TCGA cell cohorts, ANKRD24 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD24-associated genes across cancer lineages are N22899-6-C1, Trametinib, and 123829. Each is linked with ANKRD24 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD24-to-partner and partner-to-ANKRD24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N22899-6-C1 grouped by ANKRD24-low versus ANKRD24-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD24→partner) and Y-score (partner→ANKRD24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	N22899-6-C1 →	+0.249	+2.643	.034	.048	3	2
LARGE_INTESTINE	Trametinib →	-0.755	-2.745	.015	.047	3	1
LARGE_INTESTINE	123829 →	+0.616	+2.871	.025	.021	3	1
LARGE_INTESTINE	Panobinostat →	-0.625	-2.807	.012	.044	3	1
LUNG_SCLC	Rapamycin →	+0.418	+2.641	.022	.049	3	1
LUNG_SCLC	Ipatasertib →	+0.625	+2.695	.008	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

N22899-6-C1 by ANKRD24 expression — BLOOD_Leukemia

Explore this box plot interactively →