ANKRD23

Across TCGA cell cohorts, ANKRD23 mutation is significantly associated with the RNA expression of many other genes, with 271 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANKRD23-associated genes across cancer lineages are ST8SIA5, COQ5, and GPR63. Each is linked with ANKRD23 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD23-to-partner and partner-to-ANKRD23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ST8SIA5 grouped by ANKRD23-low versus ANKRD23-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD23→partner) and Y-score (partner→ANKRD23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ST8SIA5 →	+0.239	+3.184	.004	.007	3	1
LARGE_INTESTINE	COQ5 →	+0.548	+3.212	.003	.006	3	1
LARGE_INTESTINE	GPR63 →	+0.930	+3.212	<.001	.006	3	1
LARGE_INTESTINE	RAB29 →	+1.000	+3.299	<.001	.004	3	1
LARGE_INTESTINE	HELB →	+0.383	+3.212	.007	.006	3	1
LARGE_INTESTINE	C3orf20 →	+0.093	+3.584	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 271 associations by consensus.

ST8SIA5 by ANKRD23 expression — LARGE_INTESTINE

Explore this box plot interactively →