Across TCGA pan-cancer cohorts, ANKRD20A6P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ANKRD20A6P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where ANKRD20A6P RNA is repressed in tumor relative to normal tissue. In most cancer types ANKRD20A6P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA, KIRC, and LIHC are the cancer types where ANKRD20A6P tumor–normal differential expression is most reproducible.