ANKRD20A1

Across TCGA cell cohorts, ANKRD20A1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANKRD20A1-associated genes across cancer lineages are SPATA31A5, HELT, and SIAH3. Each is linked with ANKRD20A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKRD20A1-to-partner and partner-to-ANKRD20A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31A5 grouped by ANKRD20A1-low versus ANKRD20A1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKRD20A1→partner) and Y-score (partner→ANKRD20A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SPATA31A5 →	+0.013	+5.029	<.001	.006	3	1
BLOOD_Lymphoma	HELT →	+0.025	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	SIAH3 →	+0.062	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	LYPD4 →	+0.118	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SPATA31A5 by ANKRD20A1 expression — LUNG_SCLC

Explore this box plot interactively →